Will Cutting Out This Food Help Shrink Prostate?
Wednesday, November 4th, 2009
“Prostate cancer is the fourth most common malignancy among men worldwide, with an estimated 400,000 new cases diagnosed annually, accounting for 3.9 percent of all new cancer cases. 1 Epidemiologic evidence strongly suggests that dietary factors play a major role in prostate cancer progression and mortality, with protective effects associated with consumption of fruit (particularly tomatoes), vitamin E, and selenium, and increased risk linked to dairy products, meat, and fat. Dairy product consumption has been associated with prostate cancer risk in divergent populations, and several studies have investigated mechanisms that may explain these findings. This review describes studies reporting prostate cancer risk in relation to milk or dairy products generally. It does not include studies reporting only intake of individual milk derivatives, such as butter, or nutrients, such as fat.
”Prostate cancer is one of the most common malignancies worldwide, with an estimated 400,000 new cases diagnosed annually. Its incidence and mortality have been associated with milk or dairy product consumption in international and interregional correlational studies. As a result, case-control and cohort studies have further investigated this association and are described in this review. Of 12 case-control studies, six found significant associations, as did five of 11 cohort studies, with relative risk of prostate cancer among those with the most frequent dairy product consumption ranging between 1.3 and 2.5, with evidence of a dose-response relationship.
Mechanisms that may explain this association include the deleterious effect of high-calcium foods on vitamin D balance, the tendency of frequent dairy intake to increase serum insulin-like growth factor I (IGF-I) concentrations, and the effect of dairy products on testosterone concentration or activity.Two studies in northern Italy compared prostate cancer patients with hospital controls, finding increased risk of prostate cancer among those with the most frequent milk consumption.
Similarly, a study at Roswell Park Memorial Institute in Buffalo, N.Y., found an increased risk of prostate cancer with the daily consumption of three or more glasses of whole milk, compared with never drinking milk. In Montevideo, Uruguay, a comparison of prostate cancer patients with hospital controls, most of whom had other forms of cancer, found an increased risk of prostate cancer associated with drinking two or more milk servings per day, compared with having less than one serving per day. In Örebro county, Sweden, men with prostate cancer were compared with controls selected from a population register.
Higher dairy product consumption was associated with increased relative risk of prostate cancer. Dairy products may influence the incidence or progression of prostate cancer by several possible mechanisms. One for which evidence is particularly compelling is the effect of high-calcium foods on vitamin D metabolism. In several prospective studies, calcium intake has emerged as an independent predictor of prostate cancer risk.
”Dairy product consumption has also been shown to increase serum concentrations of insulin-like growth factor (IGF-I). Case-control studies in diverse populations have shown a strong and consistent association between serum IGF-I concentrations and prostate cancer risk. In men and women aged 55 to 85 years, the addition of three daily eight-ounce servings of nonfat or 1 percent milk for 12 weeks was associated with a 10 percent increase in serum IGF-I concentration (P<0.001). Mean serum IGF-I concentration among vegans was shown to be 8 percent lower than among ovolacto-vegetarians and 9 percent lower than among meat-eaters.
”Changing dietary protein sources from animal sources to plant sources has been shown to reduce serum IGF-I concentrations.Most dairy products contain substantial amounts of fat and are devoid of fiber, a combination that is likely to increase serum testosterone concentration and activity.
“Dietary factors other than dairy products are also associated with risk. Generally speaking, diets high in animal products are associated with higher risk, while those rich in plant foods, particularly tomatoes, are associated with reduced risk. Daily soymilk consumption was associated with a significant reduction in prostate cancer risk in a cohort of 13,855 Seventh-Day Adventist men.
“Isoflavones in soymilk inhibit growth of human prostate cancer cells and also inhibit 5a-reductase, an enzyme that converts testosterone to 5a-dihydrotestosterone in the prostate.42 A similar beneficial effect was demonstrated for tofu consumption. Based on experience with a case-control study in Athens, Greece, researchers calculated that the combined effect of reducing dairy consumption, substituting olive oil for other added fats, and increasing tomato intake to the levels consumed by those in the lowest risk categories could reduce prostate cancer risk in their population by 41 percent.
“Evidence from international, case-control, and cohort studies suggests that men who avoid dairy products are at lower risk for prostate cancer incidence and mortality.
“Men who choose to avoid dairy products reap other nutritional benefits, such as a reduction in total fat, saturated fat, and cholesterol intake.”
(Source pcrm.org).
Cheese and Testicular Cancer
”In October of 2003, the largest study on diet and testicular cancer ever conducted was published, studying the diets of hundreds of cancer victims. After cheese consumption, the second strongest dietary risk factor for testicular cancer seemed to be the consumption of lunch meat.” International Journal of Cancer 106 (2003): p. 934.
I believe the evidence proves that dairy consumption can contribute to an increase in prostate cancer. and mortality, with protective effects associated with consumption of fruit (particularly tomatoes), vitamin E, and selenium, and increased risk linked to dairy products, meat, and fat. Dairy product consumption has been associated with prostate cancer risk in divergent populations, and several studies have investigated mechanisms that may explain these findings. This review describes studies reporting prostate cancer risk in relation to milk or dairy products generally. It does not include studies reporting only intake of individual milk derivatives, such as butter, or nutrients, such as fat.
”Prostate cancer is one of the most common malignancies worldwide, with an estimated 400,000 new cases diagnosed annually. Its incidence and mortality have been associated with milk or dairy product consumption in international and interregional correlational studies. As a result, case-control and cohort studies have further investigated this association and are described in this review. Of 12 case-control studies, six found significant associations, as did five of 11 cohort studies, with relative risk of prostate cancer among those with the most frequent dairy product consumption ranging between 1.3 and 2.5, with evidence of a dose-response relationship. Mechanisms that may explain this association include the deleterious effect of high-calcium foods on vitamin D balance, the tendency of frequent dairy intake to increase serum insulin-like growth factor I (IGF-I) concentrations, and the effect of dairy products on testosterone concentration or activity.
Two studies in northern Italy compared prostate cancer patients with hospital controls, finding increased risk of prostate cancer among those with the most frequent milk consumption. Similarly, a study at Roswell Park Memorial Institute in Buffalo, N.Y., found an increased risk of prostate cancer with the daily consumption of three or more glasses of whole milk, compared with never drinking milk. In Montevideo, Uruguay, a comparison of prostate cancer patients with hospital controls, most of whom had other forms of cancer, found an increased risk of prostate cancer associated with drinking two or more milk servings per day, compared with having less than one serving per day. In Örebro county, Sweden, men with prostate cancer were compared with controls selected from a population register. Higher dairy product consumption was associated with increased relative risk of prostate cancer.
Dairy products may influence the incidence or progression of prostate cancer by several possible mechanisms. One for which evidence is particularly compelling is the effect of high-calcium foods on vitamin D metabolism. In several prospective studies, calcium intake has emerged as an independent predictor of prostate cancer risk.
”Dairy product consumption has also been shown to increase serum concentrations of insulin-like growth factor (IGF-I). Case-control studies in diverse populations have shown a strong and consistent association between serum IGF-I concentrations and prostate cancer risk. In men and women aged 55 to 85 years, the addition of three daily eight-ounce servings of nonfat or 1 percent milk for 12 weeks was associated with a 10 percent increase in serum IGF-I concentration (P<0.001). Mean serum IGF-I concentration among vegans was shown to be 8 percent lower than among ovolacto-vegetarians and 9 percent lower than among meat-eaters
”Changing dietary protein sources from animal sources to plant sources has been shown to reduce serum IGF-I concentrations.
Most dairy products contain substantial amounts of fat and are devoid of fiber, a combination that is likely to increase serum testosterone concentration and activity.
“Dietary factors other than dairy products are also associated with risk. Generally speaking, diets high in animal products are associated with higher risk, while those rich in plant foods, particularly tomatoes, are associated with reduced risk. Daily soymilk consumption was associated with a significant reduction in prostate cancer risk in a cohort of 13,855 Seventh-Day Adventist men.
“Isoflavones in soymilk inhibit growth of human prostate cancer cells and also inhibit 5a-reductase, an enzyme that converts testosterone to 5a-dihydrotestosterone in the prostate.42 A similar beneficial effect was demonstrated for tofu consumption. Based on experience with a case-control study in Athens, Greece, researchers calculated that the combined effect of reducing dairy consumption, substituting olive oil for other added fats, and increasing tomato intake to the levels consumed by those in the lowest risk categories could reduce prostate cancer risk in their population by 41 percent.
“Evidence from international, case-control, and cohort studies suggests that men who avoid dairy products are at lower risk for prostate cancer incidence and mortality.
“Men who choose to avoid dairy products reap other nutritional benefits, such as a reduction in total fat, saturated fat, and cholesterol intake.”
(Source pcrm.org).
Cheese and Testicular Cancer
”In October of 2003, the largest study on diet and testicular cancer ever conducted was published, studying the diets of hundreds of cancer victims. After cheese consumption, the second strongest dietary risk factor for testicular cancer seemed to be the consumption of lunch meat.” International Journal of Cancer 106 (2003): p. 934.
I believe the evidence proves that dairy consumption can contribute to an increase in prostate cancer.
Article By Danny Vierrra adapted from his News Letter
Popularity: 32% [?]
